Oncología y Cáncer Aug 18, 2026

Lactate dehydrogenase-to-lymphocyte ratio predicts overall and progression-free survival among patients with advanced small-cell lung cancer receiving first-line chemoimmunotherapy: A two-center retrospective observational study

Figura científica PMC{$pmc_id}
Cutoff value for the LLR determined using X-tile analysis. (A) X-tile plot for the LLR and overall survival. Each point in the plot represents a possible cutoff value, and the color intensity indicates the strength of the association between the LLR-based grouping and overall survival based on the log-rank chi-square statistic. The black/white circle indicates the optimal cutoff point selected by X-tile analysis. (B) Histogram showing the distribution of LLR values. Patients were divided into low- and high-LLR groups according to the optimal cutoff value of 471.5. (C) Kaplan–Meier survival curves for overall survival in patients with low and high LLR. LLR = lactate dehydrogenase-to-lymphocyte ratio.
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